New Case Series Demonstrates Potential of Aquadex Therapy for End-Stage Liver Disease Patients with Fluid Overload
“This study presents an exciting new market opportunity for Nuwellis, and we look forward to gathering additional data demonstrating how Aquadex can benefit these patients,” said
The case series assessed the utilization of aquapheresis therapy with Aquadex in the intensive care unit (ICU) setting at
- Six patients were able to receive physical therapy following treatment to help improve their mobility while in the ICU.
- Five patients were transferred out of the ICU following treatment, three of whom were discharged from the hospital.
- There were no catheter-related bloodstream infections or circuit complications attributed to aquapheresis access.
“For clinicians treating patients with end-stage liver disease, it can be an enormous challenge to safely and effectively remove fluid when patients don’t respond to or can’t tolerate diuretic therapy,” said
Patients with end-stage liver disease are currently treated with diuretics, but studies show that the longer a patient is on diuretics, the less effective they become.2,3 End-stage liver disease patients are also prone to developing ascites, which requires paracentesis – a painful procedure using a needle to remove fluid from the peritoneal cavity. In this case series, Aquadex was shown to provide a potential additional solution to mitigate these clinical gaps.
Aquadex is proven to simply, safely, and precisely remove excess fluid from patients suffering from fluid overload who have not responded to conventional medical management, including diuretics. Providers can specify and adjust the rate of fluid removed for each individual patient, resulting in a gradual reduction of excess fluid. The device’s built-in, customizable hematocrit monitoring technology provides real-time measurement of percent blood volume changes that can be tailored to individual patients’ needs. A customizable fluid removal rate is particularly important for pediatric patients who have a small amount of blood in their bodies. The Aquadex system is cleared by the
Nuwellis, Inc. (Nasdaq: NUWE) is a medical technology company dedicated to transforming the lives of patients suffering from fluid overload through science, collaboration, and innovation. The company is focused on commercializing the Aquadex SmartFlow® system for ultrafiltration therapy. Nuwellis is headquartered in
Certain statements in this release may be considered forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including without limitation, statements regarding the new market opportunities and anticipated growth in 2024 and beyond. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this release, including, without limitation, those risks associated with our ability to execute on our commercialization strategy, the possibility that we may be unable to raise sufficient funds necessary for our anticipated operations, our post-market clinical data collection activities, benefits of our products to patients, our expectations with respect to product development and commercialization efforts, our ability to increase market and physician acceptance of our products, potentially competitive product offerings, intellectual property protection, our ability to integrate acquired businesses, our expectations regarding anticipated synergies with and benefits from acquired businesses, and other risks and uncertainties described in our filings with the
2 Felker MG and Mentz RJ. J Am Coll Cardiol. 2012;59(24):2145-53.
3 Doering A, et al. Int J Emerg Med. 2017;10(17).