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                            May 5, 2020

       John Erb
       Chief Executive Officer
       CHF Solutions, Inc.
       12988 Valley View Road
       Eden Prairie, Minnesota 55344

                                                        Re: CHF Solutions, Inc.
                                                            Registration
Statement on Form S-1
                                                            Filed April 29,
2020
                                                            File No. 333-237911

       Dear Mr. Erb:

               We have limited our review of your registration statement to the
issue we have addressed
       in our comment.

              Please respond to this letter by amending your registration
statement and providing the
       requested information. If you do not believe our comment applies to your
facts and
       circumstances or do not believe an amendment is appropriate, please tell
us why in your
       response.

              After reviewing any amendment to your registration statement and
the information you
       provide in response to this comment, we may have additional comments.

       Registration Statement on Form S-1 filed April 29, 2020

       Exhibits

   1.                                                   We note that in Exhibit
5.1, counsel only opines on 1,794,906 of the 6,726,506 shares of
                                                        common stock
registered. Please have counsel amend the legal opinion to opine on all of
                                                        the shares of common
stock registered.
               We remind you that the company and its management are
responsible for the accuracy
       and adequacy of their disclosures, notwithstanding any review, comments,
action or absence of
       action by the staff.

              Refer to Rules 460 and 461 regarding requests for acceleration.
Please allow adequate
       time for us to review any amendment prior to the requested effective
date of the registration
       statement.
 John Erb
CHF Solutions, Inc.
May 5, 2020
Page 2

       Please contact Irene Paik at 202-551-6553 or Celeste Murphy at
202-551-3257 with any
questions.



                                                         Sincerely,
FirstName LastNameJohn Erb
                                                         Division of
Corporation Finance
Comapany NameCHF Solutions, Inc.
                                                         Office of Life
Sciences
May 5, 2020 Page 2
cc:       Phillip D. Torrence, Esq.
FirstName LastName